英文名字 | Human IL-22/IFN-gamma/IL-10/IL-17A FluoroSpot kit, pre-coated | ||
中文名称 | Human IL-22/IFN-gamma/IL-10/IL-17A FluoroSpot kit,pre-coated | ||
供应商 | Mabtech | ||
产品货号 | FSP-18010703-10 | ||
产品报价 | ¥78540/10plates | ||
购买方式 | 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868。 | ||
产品新闻 | ![]() |
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背景资料 | Interferon-y (IFN-y, also known as IFN-gamma, IFN-g, IFNg and Interferon-gamma) is produced mainly by activated T cells and NK cells. It is a proinflammatory cytokine that activates macrophages and endothelial cells, but it also regulates immune responses by effecting APC and T and B cells. Production of IFN-y by helper T cells as well as cytotoxic T cells is a hallmark of the TH1-type phenotype, thus, high-level production of IFN-y is typically associated with effective host defense against intracellular pathogens./Interleukin-10 (IL-10, IL10) is a pleiotropic cytokine that is produced by activated T cells and monocytes. It can modulate the functions of immune responses in both a stimulatory and an inhibitory way. IL-10 is thereby involved in the regulation of immune reactions and inflammatory responses./Interleukin-17A (IL-17A, IL17A) is a potent proinflammatory cytokine produced by activated Th17 (T-helper 17) cells and certain cells belonging to the innate immune system. In mice, IL-17 has been shown to also be produced by activated CD8+ T cells and yδ T cells. Th17 cells play an important role in autoimmune diseases and protection against bacteria and fungi. IL-17A acts on a broad range of cell types to induce expression of cytokines, chemokines and metalloproteinases. As a result, secretion of IL-17A promotes inflammatory responses, which leads to the recruitment of neutrophils, enhancement of antibody production and activation of T cells. Increased expression of IL-17A is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It is also associated with asthma, psoriasis, cancer and transplant rejection./The cytokine Interleukin-22 (IL-22, IL22) is mainly produced by activated CD4+ T-helper 17 (Th17) and T-helper 22 (Th22) cells. The IL-22 receptor is expressed on non-immune cells, particularly epithelial cells and keratinocytes, and IL-22 promotes innate immune responses versus bacterial infections in these target cells. In addition, Th22 cells have been shown to play a role in the pathophysiology of many human skin diseases. | ||
产品描述 | The FluoroSpot assay is an inventive development of the ELISpot assay and uses fluorescent detection instead of colorimetric. This allows for simultaneous detection of several analytes, which is a major advantage. The human IL-22/IFN-y/IL-10/IL-17A FluoroSpot kit is perfect for users who wish to have a convenient assay with minimized assay variability. It enables enumeration of cells secreting one, two, three and four analytes and includes low fluorescent plates pre-coated with monoclonal capture antibodies, monoclonal detection antibodies, secondary reagents conjugated to fluorophores, a fluorescence enhancer and an anti-CD28 monoclonal antibody for co-stimulation. A polyclonal activator for human T cells (mAb CD3-2) is supplied as a positive control for cytokine secretion. | ||
产品特点 | 待更新 | ||
保存建议 | 建议收到产品后2-8°C保存,有效期为12个月。 | ||
产品说明书 | ![]() |
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分享保存 | 分享按钮 | ||
其他 | Mabtech 公司是一家欧洲的集研究,开发,销售,技术支持为一体的高科技免疫生物技术公司。Mabtech公司始终专业致力于研发新的单克隆抗体,生产创新的免疫试剂和销售高品质的全配套的免疫试剂盒。公司核心业务是致力于优化发展酶联免疫斑点法技术 (ELISpot)、荧光免疫斑点法技术 (FluoroSpot) 和酶联免疫吸附试验技术 (ELISA) 等免疫学方法。作为Mabtech在中国的区域代理,ag8亚游集团科技有限公司将为中国客户提供最全面的Mabtech产品以及客户订制化服务。 | ||
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