Human IL-22/IFN-gamma/IL-10/IL-17A FluoroSpot kit，pre-coated| Human IL-22/IFN-gamma/IL-10/IL-17A FluoroSpot kit, pre-coated-细胞分析试剂盒-ag8亚游集团科技有限公司

英文名字	Human IL-22/IFN-gamma/IL-10/IL-17A FluoroSpot kit, pre-coated
中文名称	Human IL-22/IFN-gamma/IL-10/IL-17A FluoroSpot kit，pre-coated
供应商	Mabtech
产品货号	FSP-18010703-10
产品报价	￥78540/10plates
购买方式	银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868。
产品新闻
背景资料	Interferon-y (IFN-y, also known as IFN-gamma, IFN-g, IFNg and Interferon-gamma) is produced mainly by activated T cells and NK cells. It is a proinflammatory cytokine that activates macrophages and endothelial cells, but it also regulates immune responses by effecting APC and T and B cells. Production of IFN-y by helper T cells as well as cytotoxic T cells is a hallmark of the TH1-type phenotype, thus, high-level production of IFN-y is typically associated with effective host defense against intracellular pathogens./Interleukin-10 (IL-10, IL10) is a pleiotropic cytokine that is produced by activated T cells and monocytes. It can modulate the functions of immune responses in both a stimulatory and an inhibitory way. IL-10 is thereby involved in the regulation of immune reactions and inflammatory responses./Interleukin-17A (IL-17A, IL17A) is a potent proinflammatory cytokine produced by activated Th17 (T-helper 17) cells and certain cells belonging to the innate immune system. In mice, IL-17 has been shown to also be produced by activated CD8+ T cells and yδ T cells. Th17 cells play an important role in autoimmune diseases and protection against bacteria and fungi. IL-17A acts on a broad range of cell types to induce expression of cytokines, chemokines and metalloproteinases. As a result, secretion of IL-17A promotes inflammatory responses, which leads to the recruitment of neutrophils, enhancement of antibody production and activation of T cells. Increased expression of IL-17A is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It is also associated with asthma, psoriasis, cancer and transplant rejection./The cytokine Interleukin-22 (IL-22, IL22) is mainly produced by activated CD4+ T-helper 17 (Th17) and T-helper 22 (Th22) cells. The IL-22 receptor is expressed on non-immune cells, particularly epithelial cells and keratinocytes, and IL-22 promotes innate immune responses versus bacterial infections in these target cells. In addition, Th22 cells have been shown to play a role in the pathophysiology of many human skin diseases.
产品描述	The FluoroSpot assay is an inventive development of the ELISpot assay and uses fluorescent detection instead of colorimetric. This allows for simultaneous detection of several analytes, which is a major advantage. The human IL-22/IFN-y/IL-10/IL-17A FluoroSpot kit is perfect for users who wish to have a convenient assay with minimized assay variability. It enables enumeration of cells secreting one, two, three and four analytes and includes low fluorescent plates pre-coated with monoclonal capture antibodies, monoclonal detection antibodies, secondary reagents conjugated to fluorophores, a fluorescence enhancer and an anti-CD28 monoclonal antibody for co-stimulation. A polyclonal activator for human T cells (mAb CD3-2) is supplied as a positive control for cytokine secretion.
产品特点	待更新
保存建议	建议收到产品后2-8°C保存，有效期为12个月。
产品说明书
分享保存	分享按钮
其他	Mabtech 公司是一家欧洲的集研究，开发，销售，技术支持为一体的高科技免疫生物技术公司。Mabtech公司始终专业致力于研发新的单克隆抗体，生产创新的免疫试剂和销售高品质的全配套的免疫试剂盒。公司核心业务是致力于优化发展酶联免疫斑点法技术 (ELISpot)、荧光免疫斑点法技术 (FluoroSpot) 和酶联免疫吸附试验技术 (ELISA) 等免疫学方法。作为Mabtech在中国的区域代理，ag8亚游集团科技有限公司将为中国客户提供最全面的Mabtech产品以及客户订制化服务。